Dark Canyon Labs Welcomes Dr. Audrey Calderwood to the Advisory Board

Dark Canyon Labs is very pleased to announce the addition of Audrey Calderwood, MD, MS to the Advisory Board. Dr. Calderwood, a gastroenterologist and Associate Professor of Medicine at Dartmouth, is a well known leader in the field of colonoscopy preparation, and is funded by the NIH to study colonoscopy preparation. She was instrumental in the development and validation of the Boston Bowel Preparation Scale, which is now the accepted standard for assessing the cleanliness of the colon at the time of the colonoscopy procedure.

We welcome her expertise to the Advisory Board as we move forward with DCL-101, our taste-free colonoscopy pill prep and its associated AI technology.

Read more about Dr. Calderwood here.

March is Colorectal Cancer Awareness Month

Colorectal Cancer kills over 50,000 Americans every year, but it is a preventable disease with proper screening. Regular screening should begin at age 45. Due to the COVID pandemic over the last year, rates of screening for colorectal cancer have plummeted.

Screening for colorectal cancer can save your life. Don’t wait. Get screened now!

Dark Canyon Labs is working on developing a safe and effective taste-free pill prep, with dosing that can be customized for each patient. Our goal is to make the process of prepping for a colonoscopy much better for patients and healthcare professionals alike, to save more lives. Get screened and prevent colorectal cancer!

For additional information about screening and colorectal cancer:

• Colorectal Cancer Alliance

• American Cancer Society

• American Gastroenterological Association

• American College of Gastroenterology

Dark Canyon Labs Announces Positive Phase 2 Trial Results for Taste-Free Colonoscopy Prep, DCL-101, in Peer-Reviewed Publication

Dark Canyon Labs is excited to announce publication of positive Phase 2 results in Clinical and Translational Gastroenterology. View the entire article here.

Study Highlights

What is known:

• The gold standard for colonoscopy prep safety and efficacy is 4L polyethylene glycol-electrolyte solution (PEG-ELS).

• 40% of patients have known risk factors for a suboptimal prep, and 4L PEG-ELS is recommended for this population.

• The tolerability of 4L PEG-ELS is limited by its taste and volume.

What is new here:

• DCL-101 is a novel pill-based colonoscopy prep that is taste-free and compositionally identical to 4L PEG-ELS. Safety and efficacy of DCL-101 appear to be similar to 4L PEG-ELS.

• DCL-101 is significantly better tolerated than 4L PEG-ELS. 87% of patients found DCL-101 to have “no taste” or “good taste.” The vast majority of patients found DCL-101 “easy to take,” and experienced far less dread during the prep.

• Palatability has a large impact on overall colon prep tolerability.

Dark Canyon Labs Strengthens U.S. Patent for Novel Taste-Free Pill Prep, DCL-101

Dark Canyon Laboratories, LLC is pleased to report that we have received “Notice of Allowance” from the United States Patent and Trademark Office for a Continuation of our Divisional Colon Lavage System patent for the Novel DCL-101 Taste-Free Pill Prep.

This addition further strengthens the intellectual property portfolio defining our novel colonoscopy preparation technology.

The newly expanded U.S. patent joins a comprehensive list of patents already issued to Dark Canyon Labs in Japan, Australia, Canada, China, Hong Kong and the EU for a novel Colon Lavage System.

Isn't it time for a better colonoscopy prep?

Dark Canyon Labs Granted Hong Kong Patent for DCL-101 Taste-Free Pill Prep

Dark Canyon Labs was granted Hong Kong Patent No. 1167572 for development of a novel Colon Lavage System on May 22, 2020.

Dark Canyon Labs is especially pleased to announce that this Hong Kong Patent for DCL-101, a novel taste-free pill prep, used for colonoscopy preparation, joins patents for DCL-101 already issued in the US, Japan, Australia, Canada, China and the EU.