March is Colorectal Cancer Awareness Month

Colorectal Cancer kills over 50,000 Americans every year, but it is a preventable disease with proper screening. Regular screening should begin at age 45. Due to the COVID pandemic over the last year, rates of screening for colorectal cancer have plummeted.

Screening for colorectal cancer can save your life. Don’t wait. Get screened now!

Dark Canyon Labs is working on developing a safe and effective taste-free pill prep, with dosing that can be customized for each patient. Our goal is to make the process of prepping for a colonoscopy much better for patients and healthcare professionals alike, to save more lives. Get screened and prevent colorectal cancer!

For additional information about screening and colorectal cancer:

• Colorectal Cancer Alliance

• American Cancer Society

• American Gastroenterological Association

• American College of Gastroenterology

Dark Canyon Labs Announces Positive Phase 2 Trial Results for Taste-Free Colonoscopy Prep, DCL-101, in Peer-Reviewed Publication

Dark Canyon Labs is excited to announce publication of positive Phase 2 results in Clinical and Translational Gastroenterology. View the entire article here.

Study Highlights

What is known:

• The gold standard for colonoscopy prep safety and efficacy is 4L polyethylene glycol-electrolyte solution (PEG-ELS).

• 40% of patients have known risk factors for a suboptimal prep, and 4L PEG-ELS is recommended for this population.

• The tolerability of 4L PEG-ELS is limited by its taste and volume.

What is new here:

• DCL-101 is a novel pill-based colonoscopy prep that is taste-free and compositionally identical to 4L PEG-ELS. Safety and efficacy of DCL-101 appear to be similar to 4L PEG-ELS.

• DCL-101 is significantly better tolerated than 4L PEG-ELS. 87% of patients found DCL-101 to have “no taste” or “good taste.” The vast majority of patients found DCL-101 “easy to take,” and experienced far less dread during the prep.

• Palatability has a large impact on overall colon prep tolerability.

March is Colorectal Cancer Awareness Month

Colorectal cancer is the third leading cause of cancer-related deaths in men and women in the United States, and kills over 50,000 people annually. Colorectal cancer can be prevented by getting screened.

Historically, one of the obstacles of getting a screening colonoscopy has been the bad taste and tolerability of the colonoscopy prep, which must be taken prior to the procedure. Dark Canyon Labs has developed a new colonoscopy prep, DCL-101, which is a taste-free pill prep. A Phase 2 clinical trial was successfully completed, with Phase 3 to begin in the near future.

Dark Canyon Labs is determined to make a safe and effective taste-free pill prep available for patients. Our goal is to make the process of prepping for a colonoscopy much easier and to increase colonoscopy screening rates, thereby saving lives. Get screened and prevent colorectal cancer!

For more information, visit the American Society for Gastrointestinal Endoscopy.

Phase 2 Results of Dark Canyon Labs' Novel Pill Prep DCL-101 Selected as one of the "Most Innovative and Impactful Abstracts at ACG 2018"

The American College of Gastroenterology’s (ACG) Innovation & Technology Committee recently selected 22 abstracts as the “Most Innovative and Impactful Abstracts at ACG 2018”, from over 2600 abstracts that were presented at the ACG’s annual Scientific Meeting in Philadelphia, PA in October 2018.

Dark Canyon Labs’ presentation of Phase 2 study results of the Novel Pill Prep, DCL-101, was selected as one of the “Most Innovative and Impactful Abstracts at ACG 2018.”

The ACG Innovation & Technology Committee is a forum that allows members to gather information about new ideas, innovations and technologies in gastroenterology. Selecting the “Most Innovative and Impactful Abstracts at ACG 2018” allowed the Committee to highlight the clinical significance and importance of emerging technologies in gastroenterology.

See the complete ACG report here.